• br Materials and methods br Results Teeth were collected

  2018-10-20

  

  Materials and methods Results Teeth were collected from 10 female and 6 male subjects. The subject ages ranged from 6 to 13years old, with an average age of 9. All subjects were typically developing children with no suspicion of undiagnosed neurogenetic disorders. The teeth included in the stu

• Subsequently we confirmed that the gene modified clone

  2018-10-20

  

  Subsequently, we confirmed that the gene modified clone of H256 C6, termed CHMP2B IVS5AS GG-CC, remained truly pluripotent. This was demonstrated via expression analyses of key pluripotency markers on protein level (Fig. 1B). Additionally, CHMP2B IVS5AS GG-CC retained the potential to differentiate

• br Materials and methods br

  2018-10-20

  

  Materials and methods Acknowledgments This study was supported by postdoctoral research station of Central South University and funded by China Postdoctoral Science Foundation (2014M560650 to S.Z.), the National Natural Science Foundation of China (grant number 31401248 to S.Z.). We thank the

• More recently work has been performed in

  2018-10-20

  

  More recently, work has been performed in the NHP species, Macaca fasicularis (the crab-eating macaque), in which autologously transplanted iPS-derived dopamine neurons were able to survive and restore motor deficits for up to 2years (Hallett et al., 2015). However, the degree to which studies inves

• br Materials and methods br

  2018-10-20

  

  Materials and methods Acknowledgments We would like to thank Dr. Keisuke Okita and Prof. Shinya Yamanaka for providing the cyclic gmp for reprogramming. We thank I Bente Smith Thorup for excellent technical assistance in the cell culture. We thank Jeannette Schoene and Dirk A. Pflumm for cytog

• br Experimental Procedures br Acknowledgments br Introductio

  2018-10-20

  

  Experimental Procedures Acknowledgments Introduction Human pluripotent stem cells (hPSCs), including human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs), hold great promise in the fields of regenerative medicine and drug discovery. Although their practical u

• The concept of neoblast specialization at wounds is importan

  2018-10-20

  

  The concept of neoblast specialization at wounds is important in understanding planarian regeneration and opens many avenues for future inquiry. For example, how is the neoblast response tailored to the identity of missing tissues? Do specialized neoblasts amplify their population, or do specialized

• In summary this study revealed the

  2018-10-20

  

  In summary, this study revealed the unexpected capacity of Sox2 for converting reactive glial cells into induced DCX+ neurons in the injured cerebral cortex. Our work highlights the potential of NG2 glia as cellular candidates for de novo generation of new neurons in the cerebral cortex, a inhibitor

• salinomycin Tumor diameter exhibited no significant correlat

  2018-10-20

  

  Tumor diameter exhibited no significant correlation with the proportion of OCT4+/HNu+ cells. Instead, the proportion of grafted salinomycin that were OCT4+ was solely dependent on the post-transplantation observation period. In our previous study, we observed no evidence of OCT4+/HNu+ cells or tumo

• dub ubiquitin A role for PI K controlling ENPs

  2018-10-20

  

  A role for PI3K controlling ENPs fits well with current ideas of how FGF, BMP, β-catenin, and FAT4 regulate ENP self-renewal and differentiation (Figure 4C). The ENPs all receive the differentiation promoting β-catenin signal from the ureteric bud, but only the dub ubiquitin that receive a stromal

• To gain greater insight into the

  2018-10-20

  

  To gain greater insight into the broad applicability for cell delivery, HAMC was investigated for the delivery of adult mouse NSCs (Morshead et al., 1994) to the brain. Significantly more cells were observed when delivered in HAMC versus artificial cerebrospinal fluid (aCSF) controls. Moreover, the

• br Results br Discussion Pluripotent stem cells

  2018-10-20

  

  Results Discussion Pluripotent stem opioid receptors offer unprecedented potential for regenerative medicine as they can be differentiated by a specific sequence of signals to become any cell type of the body. At the same time, any cell product generated from them confers a substantial risk f

• br Results br Discussion We have successfully

  2018-10-20

  

  Results Discussion We have successfully established a human stem cell model to study the molecular mechanisms underlying MODY5. Our experimental design, which includes a non-family control hiPSC line and three independent hiPSC lines from each of the three subjects in a MODY5 family, is a well

• Retinal progenitor cells RPCs are proliferative multipotent

  2018-10-20

  

  Retinal progenitor EPZ-6438 (RPCs) are proliferative multipotent cells that produce differentiated cells in an evolutionary conserved birth order (Bassett and Wallace, 2012; Cepko et al., 1996). RPC proliferation and differentiation must be closely integrated and coordinated with eye growth for pro

• In this issue of E Biomedicine Mehta et

  2018-08-23

  

  In this issue of E-Biomedicine, Mehta et al. () present a phylogeographic study to assess the characteristics of HIV transmission in the Tijuana–San Diego crossing of the Mexico–U.S. border region. This work is a good example of how phylogenetic and phylogeographic analyses on already existing HIV s

15690 records 1046/1046 page Previous First page 上5页 1046