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br Results Karyotyping revealed chromosomal abnormalities in
2019-04-17
Results Karyotyping revealed chromosomal abnormalities in 19 of 20 metaphase spreads examined. All abnormal metaphases had a del(14)(q22), and 17 metaphases were interpreted to contain a three way translocation, t(2;5;7)(q31;q21;q11.2) and loss of all or part of chromosome 6. FISH analysis showed
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br Discussion Our case demonstrates feasibility for improvem
2019-04-17
Discussion Our case demonstrates feasibility for improvement in erythropoiesis in a patient with poor predictor of ESA/G-CSF response/growth factor refractory, low-risk MDS who was treated with sertraline for co-morbid depression. Within 100 days concurrent administration of sertraline, ESA and G
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To overcome these resistance mechanisms in APL cells
2019-04-17
To overcome these resistance mechanisms in APL cells, a number of drugs have been tested. Tamibarotene is approximately 10 times more potent than ATRA as an in vitro inducer of differentiation, and is chemically more stable than ATRA [5]. Although the precise mechanism of the combination of tamibaro
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Yang et al reported PSA triggered TRUSP biopsy in
2019-04-17
Yang et al. reported PSA triggered TRUSP biopsy in Korea. This study included 75 patients younger than 40 years of age, with PSA > 4.0 ng/mL; the PCa detection rate was 1.3% in the Korean study. In comparison, there were substantially more abnormal DRE findings and significant LUTS findings in our s
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Another mechanism is that J waves represent a
2019-04-17
Another mechanism is that J waves represent a repolarization abnormality where J waves are created by the transmural voltage gradient [16]. During myocardial ischemia, the membrane ionic currents are known to be augmented, in turn augmenting the transient outward current (Ito). Augmented Ito would r
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Although no GWAS results have been
2019-04-17
Although no GWAS results have been reported so far from Asian populations, the candidate gene approach identified SNPs in 4q25 and 1q21 as being associated with AF in Asian populations [19,20]. Conflicting data are reported in terms of 16q22; it is associated with AF in Chinese Han [37], but not in
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br Case report In July a year
2019-04-17
Case report In July 2010, a 64-year-old man visited the outpatient clinic of National Taiwan University Hospital due to progressive enlargement of right submandibular mass for months. A nasopharyngeal tumor was found by fiber optic exam, and biopsy showed a non-keratinizing undifferentiated carci
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En el cuento el protagonista es sometido a los abusos
2019-04-17
En el cuento, el protagonista es sometido thyrotropin receptor los abusos de la mercantilización del objeto artístico y de una distorsionada crítica de arte que buscan en él diversas explicaciones o justificaciones a su propia razón de ser a través de mecanismos legitimadores, enmarcados en el entor
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Seg n Auerbach la parataxis es
2019-04-17
Según Auerbach, la parataxis es un modo primitivo y anticlásico de narrar, típico de la Edad Media, que será sustituido gradualmente por maneras más modernas y finas de describir la realidad. No obstante, en fechas recientes ha vuelto phospholipase inhibitor ser practicada, por ejemplo por una serie
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By GBD region in the past
2019-04-17
By GBD region, in the past two decades, the largest increases in incidence of ischaemic stroke were in eastern Europe, central and east Asia, north and sub-Saharan Africa, and the Middle East (figure 1), with the largest increase (22%) noted in the Democratic Republic of Congo. Notably, some of the
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buy Cisplatin br CaMKII and heart failure progression CaMKII
2019-04-16
CaMKII and heart failure progression CaMKII is a multifunctional serine–threonine kinase, phosphorylating target proteins. Under resting conditions, CaMKII is inactive. A rise in intracellular Ca2+ stimulates binding of Ca2+ to calmodulin (CaM), a ubiquitous Ca2+-binding protein. The Ca2+/CaM com
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The functional analysis of this
2019-04-16
The functional analysis of this V1764fsX1786 mutation is shown in Fig. 3B; no current was observed, indicating severe loss-of-function. Although we did not investigate the mechanisms of this complete reduction in Na+ current in this mutation, Herfst et al [19]. reported a similar frameshift mutation
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Because of high suspicion of malignancy we chose endoscopic
2019-04-16
Because of high suspicion of malignancy, we chose endoscopic ultrasound (EUS) instead of MRI of the pancreas to detect the organic lesion that caused the distal CBD stricture because initial abdominal CT did not show any suspicious lesion in the pancreas. In addition, tissue sample could be obtained
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Data for each assessment point are expressed as the mean
2019-04-16
Data for each assessment point are expressed as the mean value plus standard deviation. One tailed paired t-tests were performed to analyze the effects of ibandronate treatment. Significance level was set at p Results The study included 33 patients with a variety of different primary tumors (Table
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br Discussion br Conclusions br
2019-04-16
Discussion Conclusions Conflicts of interest Introduction Catecholaminergic polymorphic ventricular tachycardia (CPVT) is induced by emotional stress or exercise in patients without organic heart disease and may be polymorphic or bidirectional (Fig. 1) [1–3]. This ventricular arrhythmia
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